Synthesis of all-trans-beta-carotene retinoids and derivatives labelled with 14C
Résumé
In this paper we report the synthesis of all-trans Retinoic acid, Retinal, Retinol specifically labelled with 14C at position 7 and all-trans Beta-carotene labelled at positions 7 and 7′, with more than 98% radiochemical purity. All products were obtained with about 15% overall yield from 14C sodium cyanide.