Article Dans Une Revue Clinical Chemistry and Laboratory Medicine Année : 2016

Preanalytical, analytical, gestational and pediatric aspects of the S100B immuno-assays

Résumé

Abstract Background: Traumatic brain injury management is a tricky issue in children and pregnant women (due to adverse effects of computer tomography). To facilitate management, we report the main analytical performances and reference ranges for blood tests for the well-established S100B biomarker in under-16 children on a DiaSorin Methods: Serum S100B concentrations were determined by chemiluminescent immunoassay on a DiaSorin Results: For children, four age-groups emerged, i.e. 0–3 months (mean: 0.97 μg/L; standard deviation (SD): 0.36; 95th percentile: 1.55), 4–9 months (mean: 0.58 μg/L; SD: 0.30; 95th: 1.18), 10–24 months (mean: 0.31 μg/L; SD: 0.12; 95th: 0.54) and 2–16 years (mean: 0.20 μg/L; SD: 0.07; 95th: 0.32). For pregnant women, serum S100B concentrations were similar to defined ranges for adults and not significantly different between trimesters on DiaSorin Conclusions: Data provided here is useful for interpreting serum S100B test results, in terms of preanalytical conditions, analytical performances, pediatric and pregnancy’ environment.

Dates et versions

hal-04885666 , version 1 (14-01-2025)

Identifiants

Citer

Damien Bouvier, Thomas Duret, Paul Rouzaire, Matthieu Jabaudon, Marion Rouzaire, et al.. Preanalytical, analytical, gestational and pediatric aspects of the S100B immuno-assays. Clinical Chemistry and Laboratory Medicine, 2016, 54 (5), ⟨10.1515/cclm-2015-0771⟩. ⟨hal-04885666⟩
0 Consultations
0 Téléchargements

Altmetric

Partager

More