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Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against Adherent-Invasive Escherichia coli Bacteria Associated with Crohn's Disease

Adeline Sivignon , Xibo Yan , Dimitri Alvarez Dorta , Richard Bonnet , Julie Bouckaert et al.
mBio, 2015, 6 (6), pp.e01298-15. ⟨10.1128/mBio.01298-15⟩
Journal articles hal-01265411v1
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Oligomannose-Rich Membranes of Dying Intestinal Epithelial Cells Promote Host Colonization by Adherent-Invasive E. coli

Tetiana Dumych , Nao Yamakawa , Adeline Sivignon , Estelle Garénaux , Stefania Robakiewicz et al.
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.00742⟩
Journal articles hal-01796957v1

Major O-glycans in the spores of two microsporidian parasites are represented by unbranched manno-oligosaccharides containing alpha-1,2 linkages.

Vanessa Taupin , Estelle Garenaux , Muriel Mazet , Emmanuel Maes , Hubert Denise et al.
Glycobiology, 2007, 17 (1), pp.56-67. ⟨10.1093/glycob/cwl050⟩
Journal articles hal-00529950v1
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Differentiation of Crohn’s Disease-Associated Isolates from Other Pathogenic Escherichia coli by Fimbrial Adhesion under Shear Force

Sabine Szunerits , Oleksandr Zagorodko , Virginie Cogez , Tetiana Dumych , Thibaut Chalopin et al.
Biology, 2016, 5 (2), ⟨10.3390/biology5020014⟩
Journal articles hal-01741244v1

Cellulose fonctionnalisée par un heptil-mannose: un nouvel outil thérapeutique et diagnostic ciblant les Escherichia coli adhérents et invasifs

Adeline Sivignon , Madeleine Cauwel , Clarisse Bridot , Medy C. Nongbe , Sebastien G. Gouin et al.
15e congrès naional de la SFM, Sep 2019, PARIS, France
Conference poster hal-02196790v1

The Antiadhesive Strategy in Crohn′s Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut

Dimitri Alvarez Dorta , Adeline Sivignon , Thibaut Chalopin , Tetiana Dumych , Goedele Roos et al.
ChemBioChem, 2016, 17 (10), pp.936-952. ⟨10.1002/cbic.201600018⟩
Journal articles istex hal-02077036v1

Thiazolylaminomannosides As Potent Antiadhesives of Type 1 Piliated Escherichia coli Isolated from Crohn’s Disease Patients

Sami Brument , Adeline Sivignon , Tetiana Dumych , Nicolas Moreau , Goedele Roos et al.
Journal of Medicinal Chemistry, 2013, 56 (13), pp.5395 - 5406. ⟨10.1021/jm400723n⟩
Journal articles hal-01931359v1

Physiochemical tuning of potent escherichia coli anti-adhesives by microencapsulation and methylene homologation

Dimitri Alvarez Dorta , Thibaut Chalopin , Adeline Sivignon , Jerome de Ruyck , Tetiana I. Dumych et al.
52. International Conference on Medicinal Chemistry (RICT) of the French-Medicinal-Chemistry-Society (SCT) - Interfacing Chemical Biology and Drug Discovery, Jul 2016, Caen, France. pp.13, ⟨10.1002/cmdc.201700061⟩
Conference papers hal-01607981v1

The Vat-AIEC protease promotes crossing of the intestinal mucus layer by Crohn's disease-associated Escherichia coli

Lucie Gibold , Estelle Garénaux , Guillaume Dalmasso , Camille Gallucci , David Cia et al.
Cellular Microbiology, 2016, 18 (5), pp.617 - 631. ⟨10.1111/cmi.12539⟩
Journal articles hal-01926372v1

Inhibition profiles of mono- and polyvalent FimH antagonists against 10 different Escherichia coli strains

T. Chalopin , Y. Brissonnet , Adeline Sivignon , D. Deniaud , L. Cremet et al.
Organic & Biomolecular Chemistry, 2015, 13 (46), pp.11369 - 11375. ⟨10.1039/c5ob01581b⟩
Journal articles hal-01931394v1

Two scales of inflation at Lastarria-Cordon del Azufre volcanic complex, central Andes, revealed from ASAR-ENVISAT interferometric data

J.-L. Froger , D. Remy , S. Bonvalot , Delphine Legrand
Earth and Planetary Science Letters, 2007, 255, pp.148-163. ⟨10.1016/J.EPSL.2006.12.012⟩
Journal articles istex hal-00322023v1

From mechanisms of bacterial binding to glycomimics

Tetiana Dumych , Adeline Sivignon , Antonio Bongiovanni , Nao Yamakawa , Fabrice Bray et al.
GLYCOALP, Jun 2019, Genoble, France
Conference papers hal-02196745v1

Cellulose fonctionnalisée par un heptyl-mannose: un nouvel outil thérapeutique et diagnostic ciblant les Escherichia coli adherents et invasifs

Adeline Sivignon , Madeleine Cauwel , Clarisse Bridot , Medy C. Nongbe , David Deniaud et al.
15eme congres national de la SFM, Sep 2019, Paris, France
Conference poster hal-02338687v1

Analysis of the sigma(E) Regulon in Crohn's Disease-Associated Escherichia coli Revealed Involvement of the waaWVL Operon in Biofilm Formation

Benoit Chassaing , Estelle Garénaux , Jessica Carrière , Nathalie Rolhion , Yann Guerardel et al.
Journal of Bacteriology, 2015, 197 (8), pp.1451-1465. ⟨10.1128/JB.02499-14⟩
Journal articles hal-02631034v1

Transformed Waldenström macroglobulinaemia: clinical presentation and outcome. A multi-institutional retrospective study of 77 cases from the French Innovative Leukemia Organization (FILO)

Eric Durot , Cécile Tomowiak , Sophie Michallet , Jehan Dupuis , Bénédicte Hivert et al.
British Journal of Haematology, 2017, 179 (3), pp.439 - 448. ⟨10.1111/bjh.14881⟩
Journal articles hal-01655985v1

The potential of FimH as a novel therapeutic target for the treatment of Crohn’s disease

Adeline Sivignon , Julie Bouckaert , Julien Bernard , Sebastien G. Gouin , Nicolas Barnich et al.
Expert Opinion on Therapeutic Targets, 2017, 21 (9), pp.837 - 847. ⟨10.1080/14728222.2017.1363184⟩
Journal articles hal-01633566v1
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Heptylmannose-functionalized cellulose for the binding and specific detection of pathogenic E. coli

Madeleine Cauwel , Adeline Sivignon , Clarisse Bridot , Medy Nongbe , David Deniaud et al.
Chemical Communications, 2019, 55 (68), pp.10158-10161. ⟨10.1039/c9cc05545b⟩
Journal articles hal-02360573v1

Functional and biophysical analyses of the class XIV Toxoplasma gondii myosin D.

Angelika Herm-Götz , Frédéric Delbac , Stefan Weiss , Miklos Nyitrai , Rolf Stratmann et al.
Journal of Muscle Research and Cell Motility, 2006, 27 (2), pp.139-51. ⟨10.1007/s10974-005-9046-1⟩
Journal articles hal-00527175v1
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Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches

Emmanuelle Soleilhac , Loraine Brillet-Guéguen , Véronique V. Roussel , Renaud Prudent , Bastien Touquet et al.
International Journal of Molecular Sciences, 2018, 19 (10), pp.3085. ⟨10.3390/ijms19103085⟩
Journal articles hal-02106151v1

A library of heptyl mannose-functionalized copolymers with distinct compositions, microstructures and neighboring non-sugar motifs as potent antiadhesives of type 1 piliated E. coli

Xibo Yan , Adeline Sivignon , Nicolas Barnich , Sébastien G Gouin , Julie Bouckaert et al.
Polymer Chemistry, 2016, 7 (15), pp.2674-2683. ⟨10.1039/c6py00118a⟩
Journal articles hal-01396465v1