Search - Université Clermont Auvergne Access content directly

Filter your results

75 Results
Domains :

Antibody functionalization for pretargeted imaging and radiotherapy Nanotechnology for targeted personalized medicines and theranostics

Taiariol Ludivine , Aurélie Rondon , Mercedes Quintana , Sophie Besse , Isabelle Navarro-Teulon et al.
E-MRS 2018 Spring Meeting, Jun 2018, Strasbourg, France
Conference papers hal-01938907v1

(2 R ,3 S )-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanoic acid chloride monohydrate

Vincent Gaumet , Valérie Weber , Valery Zaitsev , Michel Madesclaire
Acta Crystallographica Section E : Structure Reports Online [2001-2014], 2008, 64 (6), pp.o1003-o1004. ⟨10.1107/S1600536808012750⟩
Journal articles hal-02885166v1

Development of a freeze-dried kit formulation for the preparation of 99m Tc-NTP 15-5, a radiotracer for scintigraphic imaging of proteoglycans

Aurélien Vidal , Vincent Gaumet , Marie-Josephe Galmier , Sophie Besse , Fernand Leal et al.
Applied Radiation and Isotopes, 2015, 101, pp.1-9. ⟨10.1016/j.apradiso.2015.03.010⟩
Journal articles hal-01961372v1

Synthesis and Biological Evaluation of New Quinoxaline Derivatives of ICF01012 as Melanoma-Targeting Probes

Emmanuel Moreau , Radhia El Aissi , Jianrong Liu , Sophie Besse , Damien Canitrot et al.
ACS Medicinal Chemistry Letters, 2014, 5 (5), pp.468 - 473. ⟨10.1021/ml400468x⟩
Journal articles hal-01677548v1

Radiomarquage du NTP 15-5 ciblant les protéoglycanes pour l’imagerie TEP des pathologies du cartilage : comparaison d’un traceur TEP à un traceur TEMP

C. Valla , V. Gaumet , E. Jouberton , Philippe Auzeloux , F. Degoul et al.
Médecine Nucléaire - Imagerie Fonctionnelle et Métabolique, 2017, 41 (3), pp.160 - 161. ⟨10.1016/j.mednuc.2017.02.061⟩
Journal articles hal-01677505v1

Design, Synthesis, Biological Evaluation, and Structure–Activity Relationships of Substituted Phenyl 4-(2-Oxoimidazolidin-1-yl)benzenesulfonates as New Tubulin Inhibitors Mimicking Combretastatin A-4

Emmanuel Moreau , Sébastien Fortin , Lianhu Wei , Jacques Lacroix , Marie-France Côté et al.
Journal of Medicinal Chemistry, 2011, 54 (13), pp.4559 - 4580. ⟨10.1021/jm200488a⟩
Journal articles hal-01677554v1

Mechanism of action of N-phenyl-N′-(2-chloroethyl)ureas in the colchicine-binding site at the interface between α- and β-tubulin

Emmanuel Moreau , Sébastien Fortin , Lianhu Wei , Philippe Labrie , Éric Petitclerc et al.
Bioorganic and Medicinal Chemistry, 2009, 17 (10), pp.3690 - 3697. ⟨10.1016/j.bmc.2009.03.056⟩
Journal articles hal-01677570v1

[(2 R ,3 R )-3-(4-Nitrophenyl)aziridin-2-yl]methanol monohydrate

Vincent Gaumet , C. Denis , F. Leal , M. Madesclaire , V.P. Zaitsev et al.
Acta Crystallographica Section E : Structure Reports Online [2001-2014], 2013, 69 (6), pp.o927-o927. ⟨10.1107/S1600536813013391⟩
Journal articles hal-02885206v1

A comparative molecular field and comparative molecular similarity indices analyses (CoMFA and CoMSIA) of N-phenyl-N′-(2-chloroethyl)ureas targeting the colchicine-binding site as anticancer agents

Emmanuel Moreau , Sébastien Fortin , Philippe Labrie , Lianhu Wei , Lakshmi P Kotra et al.
Bioorganic and Medicinal Chemistry, 2008, 16 (4), pp.1914 - 1926. ⟨10.1016/j.bmc.2007.11.004⟩
Journal articles hal-01677579v1

Synthesis, radiofluorination and pharmacological evaluation of a fluoromethyl spirocyclic PET tracer for central σ1 receptors and comparison with fluoroalkyl homologs

Aurélie Maisonial-Besset , Aurélie Maisonial , Eva Grosse Maestrup , Christian Wiese , Achim Hiller et al.
Bioorganic and Medicinal Chemistry, 2012, 20 (1), pp.257 - 269. ⟨10.1016/j.bmc.2011.11.002⟩
Journal articles hal-01677635v1
Image document

Base/cryptand/metal-free automated nucleophilic radiofluorination of [ 18 F]FDOPA from iodonium salts: importance of hydrogen carbonate counter ion

Aurélie Maisonial-Besset , Audrey Serre , Ali Ouadi , Sébastien Schmitt , Damien Canitrot et al.
European Journal of Organic Chemistry, 2018, 2018 (48), pp.7058-7065. ⟨10.1002/ejoc.201801608⟩
Journal articles hal-02343361v1

N-Phenyl-N′-(2-chloroethyl)ureas (CEU) as potential antineoplastic agents. Part 2: Role of ω-hydroxyl group in the covalent binding to β-tubulin

Emmanuel Moreau , Sébastien Fortin , Alexandre Patenaude , Michel Desjardins , Jacques Lacroix et al.
Bioorganic and Medicinal Chemistry, 2007, 15 (3), pp.1430 - 1438. ⟨10.1016/j.bmc.2006.11.005⟩
Journal articles hal-01677583v1

Imidazonaphthyridine systems (part 2): Functionalization of the phenyl ring linked to the pyridine pharmacophore and its replacement by a pyridinone ring produces intriguing differences in cytocidal activity

Emmanuel Moreau , Nicolas Masurier , Eric Debiton , Alicia Jacquemet , Antoine Bussière et al.
European Journal of Medicinal Chemistry, 2012, 52, pp.137 - 150. ⟨10.1016/j.ejmech.2012.03.011⟩
Journal articles hal-01677549v1

Characterization of the Covalent Binding of N-Phenyl-N'-(2-chloroethyl)ureas to -Tubulin: Importance of Glu198 in Microtubule Stability

Emmanuel Moreau , S. Fortin , B. Bouchon , C. Chambon , J. Lacroix et al.
Journal of Pharmacology and Experimental Therapeutics, 2011, 336 (2), pp.460 - 467. ⟨10.1124/jpet.110.171082⟩
Journal articles hal-01677562v1

Optimized N-phenyl-N′-(2-chloroethyl)ureas as potential antineoplastic agents: Synthesis and growth inhibition activity

Emmanuel Moreau , Sébastien Fortin , Michel Desjardins , Jean L C Rousseau , Eric Petitclerc et al.
Bioorganic and Medicinal Chemistry, 2005, 13 (24), pp.6703 - 6712. ⟨10.1016/j.bmc.2005.07.048⟩
Journal articles hal-01677590v1

Heterocyclization of Functionalized Vinylic Derivatives of Imidazo[1,2- a ]pyridines

Emmanuel Moreau , Jean Chezal , Gregory Delmas , Alain Gueiffier , Yves Blache et al.
Journal of Organic Chemistry, 2001, 66 (20), pp.6576 - 6584. ⟨10.1021/jo015582x⟩
Journal articles istex hal-01677665v1

Synthesis of Polyfused Heterocycle Derivatives Containing the Dipyridoimidazole Core by Friedländer’s Reaction: Access to Analogs of Ellipticine

Emmanuel Moreau , Jean-Claude Teulade , Nicolas Desbois , Jean-Michel J.-M. Chezal , Florence Fauvelle et al.
Heterocycles, 2005, 65 (5), ⟨10.3987/COM-05-10354⟩
Journal articles hal-01677674v1

Radiosynthesis and Radiotracer Properties of a 7-(2-[18F]Fluoroethoxy)-6-methoxypyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET

Aurélie Maisonial-Besset , Uta Funke , Winnie Deuther-Conrad , Gregor Schwan , Aurélie Maisonial et al.
Pharmaceuticals Policy and Law, 2012, 5 (12), pp.169 - 188. ⟨10.3390/ph5020169⟩
Journal articles hal-01677646v1


G. Blain , Johan Vandenborre , A. Bongrand , G.R. Fois , Arnaud Guertin et al.
FRPT 2021, Dec 2021, Vienne, Austria. pp.S31, ⟨10.1016/S1120-1797(22)01500-9⟩
Conference papers in2p3-03616960v1

Hydrogen peroxide formation to investigate the radiolytic ROS production mechanism under proton FLASH conditions

Vincent Fiegel , Guillaume Blain , Manon Evin , Quentin Mouchard , Charbel Koumeir et al.
Assemblée Générale du GdR MI2B, GdR MI2B, Jun 2022, Orsay, France
Conference papers hal-03963165v1
Image document

Radiolytic ROS production mechanism under proton flash conditions : combination of experimental and simulation investigation

Vincent Fiegel , Giovanna Rosa Fois , Guillaume Blain , Manon Evin , Quentin Mouchard et al.
2nd Flash Radiotherapy and Particle Therapy Conference (FRPT 2022), Nov 2022, Barcelona, Spain
Conference poster hal-03901615v1

Macrocyclic complexes, their process of preparation and use as PET imaging agents

Vincent Gaumet , Claire Denis , Aurélien Vidal , Philippe Auzeloux , Jean-Claude Madelmont et al.
France, Patent n° : WO2016016272 (A1). 2016
Patents hal-02885526v1

Massive Cell Vacuolization Induced by Organic Amines Such as Procainamide

Emmanuel Moreau , G. Morissette
Journal of Pharmacology and Experimental Therapeutics, 2004, 310 (1), pp.395 - 406. ⟨10.1124/jpet.104.066084⟩
Journal articles hal-01677592v1
Image document

An integrated approach combining soil profile, records and tree ring analysis to identify the origin of environmental contamination in a former uranium mine (Rophin, France)

A. Martin , Y. Hassan-Loni , A. Fichtner , O. Péron , Karine David et al.
Science of the Total Environment, 2020, 747, pp.141295. ⟨10.1016/j.scitotenv.2020.141295⟩
Journal articles hal-03095931v1

Stereoselective synthesis of (E)-N,N-diethyl-3-(imidazo[1,2-a]pyrid-2-yl)-2-(phenylsulfonyl)propenamide

S. Céard , D. Roche , Vincent Gaumet , D. Gardette , J. Metin et al.
Journal of Molecular Structure, 2002, 608 (1), pp.27-33. ⟨10.1016/S0022-2860(01)00919-X⟩
Journal articles istex hal-02885118v1

Novel imidazo[1,2-a]naphthyridinic systems (part 1): Synthesis, antiproliferative and DNA-intercalating activities

Emmanuel Moreau , Mounir Andaloussi , Nicolas Masurier , Jacques Lacroix , René C Gaudreault et al.
European Journal of Medicinal Chemistry, 2008, 43 (11), pp.2505 - 2517. ⟨10.1016/j.ejmech.2008.02.017⟩
Journal articles istex hal-01677576v1

Enhancement of cationic conductivity in some heptafluorozirconates due to a paddle-wheel mechanism

Vincent Gaumet , C. Latouche , D Avignant , J. Dupuis
Solid State Ionics, 1994, 74 (1-2), pp.29-35. ⟨10.1016/0167-2738(94)90433-2⟩
Journal articles istex hal-02883790v1

Synthesis of carbamoylpyridine and imidazo[1,5-a]pyridin-1,3-diones via ortho-acetalhydantoin intermediates

Jean Chezal , Emmanuel Moreau , Nicolas Desbois , Yves Blache , Olivier Chavignon et al.
Tetrahedron Letters, 2004, 45 (3), pp.553 - 556. ⟨10.1016/j.tetlet.2003.10.200⟩
Journal articles istex hal-01677650v1

Segmentation of amyloid-β plaques in three mouse models of Alzheimer’s disease using X-ray phase contrast-computed tomography

Coralie Gislard , Carlie Boisvert , Cécile Olivier , Françoise Peyrin , Marlène Wiart et al.
European Molecular Imaging Meeting, Mar 2019, Glasgow, United Kingdom
Conference papers hal-02121424v1
Image document

Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

Jianrong Liu , Aurelie Maisonial-Besset , Barbara Wenzel , Damien Canitrot , Ariane Baufond et al.
European Journal of Medicinal Chemistry, 2017, 136, pp.548 - 560. ⟨10.1016/j.ejmech.2017.03.091⟩
Journal articles hal-01671041v1