<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04849290</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-03T08:52:32+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Involvement of Nerve Growth Factor and Tyrosine Kinase type A Receptor signaling pathways in Arthritis in knock-in TrkA/C mice: multimodal approach</title>
            <author role="crp">
              <persName>
                <forename type="first">Lauriane</forename>
                <surname>Delay</surname>
              </persName>
              <email type="md5">8ac3b4141bea4a36283e2bf0d08a0986</email>
              <email type="domain">gmail.com</email>
              <idno type="idhal" notation="string">lauriane-delay</idno>
              <idno type="idhal" notation="numeric">799745</idno>
              <idno type="halauthorid" notation="string">1562869-799745</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-5466-9856</idno>
              <affiliation ref="#struct-491236"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Julie</forename>
                <surname>Barbier</surname>
              </persName>
              <email type="md5">f059f1c40453f58341e02879e6cefcbd</email>
              <email type="domain">uhb.fr</email>
              <idno type="idhal" notation="string">julie-barbier</idno>
              <idno type="idhal" notation="numeric">1320824</idno>
              <idno type="halauthorid" notation="string">724069-1320824</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-7177-3236</idno>
              <affiliation ref="#struct-491236"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Ludivine</forename>
                <surname>Boudieu</surname>
              </persName>
              <idno type="halauthorid">1041401-0</idno>
              <affiliation ref="#struct-491236"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Youssef</forename>
                <surname>Aissouni</surname>
              </persName>
              <email type="md5">7f18d25f924411c002d4cf45855323c6</email>
              <email type="domain">inserm.fr</email>
              <idno type="idhal" notation="string">youssefaissouni</idno>
              <idno type="idhal" notation="numeric">1320045</idno>
              <idno type="halauthorid" notation="string">2527658-1320045</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/K-2254-2015</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/K-2254-2015</idno>
              <affiliation ref="#struct-491236"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Denis</forename>
                <surname>Ardid</surname>
              </persName>
              <email type="md5">387a5d09392271b72d98856e90091b13</email>
              <email type="domain">uca.fr</email>
              <idno type="idhal" notation="string">denis-ardid</idno>
              <idno type="idhal" notation="numeric">1318779</idno>
              <idno type="halauthorid" notation="string">658853-1318779</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-4320-7338</idno>
              <affiliation ref="#struct-491236"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">A.</forename>
                <surname>Briat</surname>
              </persName>
              <email type="md5">a4480f831296e9bd054f86d03c41ad57</email>
              <email type="domain">uca.fr</email>
              <idno type="idhal" notation="string">arnaud-briat</idno>
              <idno type="idhal" notation="numeric">743999</idno>
              <idno type="halauthorid" notation="string">49187-743999</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/X-8543-2019</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6636-7444</idno>
              <affiliation ref="#struct-490689"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Philippe</forename>
                <surname>Auzeloux</surname>
              </persName>
              <email type="md5">1947219873dfadb3630ddc5250da5d83</email>
              <email type="domain">uca.fr</email>
              <idno type="idhal" notation="string">philippe-auzeloux</idno>
              <idno type="idhal" notation="numeric">741549</idno>
              <idno type="halauthorid" notation="string">34925-741549</idno>
              <idno type="IDREF">https://www.idref.fr/120997517</idno>
              <affiliation ref="#struct-490689"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Elisabeth</forename>
                <surname>Miot-Noirault</surname>
              </persName>
              <email type="md5">8e153300ebd917e4bbabe1d7c1291bb0</email>
              <email type="domain">inserm.fr</email>
              <idno type="idhal" notation="numeric">941843</idno>
              <idno type="halauthorid" notation="string">713063-941843</idno>
              <affiliation ref="#struct-490689"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Aziz</forename>
                <surname>Moqrich</surname>
              </persName>
              <email type="md5">38966b67a3a2acfdf4eb68b897c319d7</email>
              <email type="domain">univ-amu.fr</email>
              <idno type="idhal" notation="string">aziz-moqrich</idno>
              <idno type="idhal" notation="numeric">17185</idno>
              <idno type="halauthorid" notation="string">13276-17185</idno>
              <idno type="IDREF">https://www.idref.fr/147499992</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1937-1675</idno>
              <affiliation ref="#struct-199397"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Fabien</forename>
                <surname>Marchand</surname>
              </persName>
              <email type="md5">d6757db9fda7bda77380b6794b14e7af</email>
              <email type="domain">uca.fr</email>
              <idno type="idhal" notation="string">fabien-marchand</idno>
              <idno type="idhal" notation="numeric">1188434</idno>
              <idno type="halauthorid" notation="string">607156-1188434</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/K-1285-2015</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-3620-6943</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/K-1285-2015</idno>
              <affiliation ref="#struct-491236"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Lauriane</forename>
                <surname>Delay</surname>
              </persName>
              <email type="md5">8ac3b4141bea4a36283e2bf0d08a0986</email>
              <email type="domain">gmail.com</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2024-12-19 15:49:05</date>
              <date type="whenModified">2025-07-09 10:25:32</date>
              <date type="whenReleased">2024-12-20 09:37:21</date>
              <date type="whenProduced">2017-11-03</date>
              <date type="whenEndEmbargoed">2024-12-19</date>
              <ref type="file" target="https://uca.hal.science/hal-04849290v1/document">
                <date notBefore="2024-12-19"/>
              </ref>
              <ref type="file" subtype="author" n="1" target="https://uca.hal.science/hal-04849290v1/file/Poster%20ACR%202017%20Lauriane%20Delay%20Version%20finale.pdf" id="file-4849290-4220969">
                <date notBefore="2024-12-19"/>
              </ref>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="1179803">
                <persName>
                  <forename>Lauriane</forename>
                  <surname>Delay</surname>
                </persName>
                <email type="md5">8ac3b4141bea4a36283e2bf0d08a0986</email>
                <email type="domain">gmail.com</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04849290</idno>
            <idno type="halUri">https://uca.hal.science/hal-04849290</idno>
            <idno type="halBibtex">delay:hal-04849290</idno>
            <idno type="halRefHtml">&lt;i&gt;ACR/ARHP Annual Meeting&lt;/i&gt;, Nov 2017, San Diego (CA), United States. &lt;a target="_blank" href="https://acrabstracts.org/abstract/involvement-of-receptor-tyrosine-kinase-a-signaling-in-rhumatoid-arthritis-using-trkac-knock-in-mice-a-multimodal-approach/"&gt;&lt;/a&gt;</idno>
            <idno type="halRef">ACR/ARHP Annual Meeting, Nov 2017, San Diego (CA), United States. </idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by/4.0/">CC BY 4.0 - Attribution<ref corresp="#file-4849290-4220969"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="PRES_CLERMONT">Université de Clermont</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-AMU">Aix Marseille Université</idno>
            <idno type="stamp" n="ND" corresp="PRES_CLERMONT">Neuro-Dol</idno>
            <idno type="stamp" n="PSL">Université Paris sciences et lettres</idno>
            <idno type="stamp" n="IMOST" corresp="PRES_CLERMONT">Imagerie Moléculaire et Stratégies Théranostiques</idno>
            <idno type="stamp" n="CDF-PSL" corresp="PSL">Collège de France - PSL </idno>
            <idno type="stamp" n="IBDM">IBDM - Institut de Biologie du Développement de Marseille</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="invited" n="0">No</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
            <note type="proceedings" n="0">No</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Involvement of Nerve Growth Factor and Tyrosine Kinase type A Receptor signaling pathways in Arthritis in knock-in TrkA/C mice: multimodal approach</title>
                <author role="crp">
                  <persName>
                    <forename type="first">Lauriane</forename>
                    <surname>Delay</surname>
                  </persName>
                  <email type="md5">8ac3b4141bea4a36283e2bf0d08a0986</email>
                  <email type="domain">gmail.com</email>
                  <idno type="idhal" notation="string">lauriane-delay</idno>
                  <idno type="idhal" notation="numeric">799745</idno>
                  <idno type="halauthorid" notation="string">1562869-799745</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-5466-9856</idno>
                  <affiliation ref="#struct-491236"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Julie</forename>
                    <surname>Barbier</surname>
                  </persName>
                  <email type="md5">f059f1c40453f58341e02879e6cefcbd</email>
                  <email type="domain">uhb.fr</email>
                  <idno type="idhal" notation="string">julie-barbier</idno>
                  <idno type="idhal" notation="numeric">1320824</idno>
                  <idno type="halauthorid" notation="string">724069-1320824</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-7177-3236</idno>
                  <affiliation ref="#struct-491236"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Ludivine</forename>
                    <surname>Boudieu</surname>
                  </persName>
                  <idno type="halauthorid">1041401-0</idno>
                  <affiliation ref="#struct-491236"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Youssef</forename>
                    <surname>Aissouni</surname>
                  </persName>
                  <email type="md5">7f18d25f924411c002d4cf45855323c6</email>
                  <email type="domain">inserm.fr</email>
                  <idno type="idhal" notation="string">youssefaissouni</idno>
                  <idno type="idhal" notation="numeric">1320045</idno>
                  <idno type="halauthorid" notation="string">2527658-1320045</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/K-2254-2015</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/K-2254-2015</idno>
                  <affiliation ref="#struct-491236"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Denis</forename>
                    <surname>Ardid</surname>
                  </persName>
                  <email type="md5">387a5d09392271b72d98856e90091b13</email>
                  <email type="domain">uca.fr</email>
                  <idno type="idhal" notation="string">denis-ardid</idno>
                  <idno type="idhal" notation="numeric">1318779</idno>
                  <idno type="halauthorid" notation="string">658853-1318779</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-4320-7338</idno>
                  <affiliation ref="#struct-491236"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">A.</forename>
                    <surname>Briat</surname>
                  </persName>
                  <email type="md5">a4480f831296e9bd054f86d03c41ad57</email>
                  <email type="domain">uca.fr</email>
                  <idno type="idhal" notation="string">arnaud-briat</idno>
                  <idno type="idhal" notation="numeric">743999</idno>
                  <idno type="halauthorid" notation="string">49187-743999</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/X-8543-2019</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6636-7444</idno>
                  <affiliation ref="#struct-490689"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Philippe</forename>
                    <surname>Auzeloux</surname>
                  </persName>
                  <email type="md5">1947219873dfadb3630ddc5250da5d83</email>
                  <email type="domain">uca.fr</email>
                  <idno type="idhal" notation="string">philippe-auzeloux</idno>
                  <idno type="idhal" notation="numeric">741549</idno>
                  <idno type="halauthorid" notation="string">34925-741549</idno>
                  <idno type="IDREF">https://www.idref.fr/120997517</idno>
                  <affiliation ref="#struct-490689"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Elisabeth</forename>
                    <surname>Miot-Noirault</surname>
                  </persName>
                  <email type="md5">8e153300ebd917e4bbabe1d7c1291bb0</email>
                  <email type="domain">inserm.fr</email>
                  <idno type="idhal" notation="numeric">941843</idno>
                  <idno type="halauthorid" notation="string">713063-941843</idno>
                  <affiliation ref="#struct-490689"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Aziz</forename>
                    <surname>Moqrich</surname>
                  </persName>
                  <email type="md5">38966b67a3a2acfdf4eb68b897c319d7</email>
                  <email type="domain">univ-amu.fr</email>
                  <idno type="idhal" notation="string">aziz-moqrich</idno>
                  <idno type="idhal" notation="numeric">17185</idno>
                  <idno type="halauthorid" notation="string">13276-17185</idno>
                  <idno type="IDREF">https://www.idref.fr/147499992</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1937-1675</idno>
                  <affiliation ref="#struct-199397"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Fabien</forename>
                    <surname>Marchand</surname>
                  </persName>
                  <email type="md5">d6757db9fda7bda77380b6794b14e7af</email>
                  <email type="domain">uca.fr</email>
                  <idno type="idhal" notation="string">fabien-marchand</idno>
                  <idno type="idhal" notation="numeric">1188434</idno>
                  <idno type="halauthorid" notation="string">607156-1188434</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/K-1285-2015</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-3620-6943</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/K-1285-2015</idno>
                  <affiliation ref="#struct-491236"/>
                </author>
              </analytic>
              <monogr>
                <meeting>
                  <title>ACR/ARHP Annual Meeting</title>
                  <date type="start">2017-11-03</date>
                  <date type="end">2017-11-08</date>
                  <settlement>San Diego (CA)</settlement>
                  <country key="US">United States</country>
                </meeting>
                <respStmt>
                  <resp>conferenceOrganizer</resp>
                  <name>American College of Rheumatology (ACR) / Association of Rheumatology Health Professionals (ARHP)</name>
                </respStmt>
                <imprint/>
              </monogr>
              <ref type="publisher">https://acrabstracts.org/abstract/involvement-of-receptor-tyrosine-kinase-a-signaling-in-rhumatoid-arthritis-using-trkac-knock-in-mice-a-multimodal-approach/</ref>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Rheumatoid Arthritis</term>
                <term xml:lang="en">Pain</term>
                <term xml:lang="en">NGF</term>
                <term xml:lang="en">TrkA</term>
              </keywords>
              <classCode scheme="halDomain" n="scco.neur">Cognitive science/Neuroscience</classCode>
              <classCode scheme="halDomain" n="sdv.mhep.phy">Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]</classCode>
              <classCode scheme="halDomain" n="sdv.neu.nb">Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology</classCode>
              <classCode scheme="halDomain" n="sdv.sp.pharma">Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology</classCode>
              <classCode scheme="halTypology" n="POSTER">Conference poster</classCode>
              <classCode scheme="halOldTypology" n="POSTER">Conference poster</classCode>
              <classCode scheme="halTreeTypology" n="POSTER">Conference poster</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Background/Purpose:  Rheumatoid Arthritis (RA) is an autoimmune disease characterized by articular inflammation, cartilage and bone alterations and is commonly associated with chronic pain difficult to treat with currents therapies. Target Nerve Growth Factor (NGF), a specific neurotrophin involved in initiation and maintenance of pain, has been already considered as a promising treatment of rheumatoid arthritis symptoms. But, due to the pleiotropic action of NGF, target this neurotrophin conducts to substantial sides’ effect. Our aim is to better understand the involvement of specific intracellular signaling pathways activated by the NGF receptor, the tyrosine kinase type A (TrkA), in the pathophysiology of RA and associated pain symptoms in order to find a more specific modulator downstream NGF. Methods: We performed a multimodal study in knock-in TrkA/C mice expressing a chimeric receptor composed by the native extracellular part of TrkA and the functional transmembrane and intracellular part of the tyrosine kinase type C receptor (TrkC) of the neurotrophin 3 (NT3). We have followed in adjuvant induced-arthritis mice model nociceptive behavior such as mechanical allodynia using von Frey test and thermal hyperalgesia using paw immersion test. In vivo alterations were analyzed with scintigraphic imaging with 99mTc-NTP 15-5 and 99mTc-HMDP, two specific radiotracers of cartilage and bone remodeling respectively. Results: Our results showed a specific decrease of mechanical allodynia without affecting thermal hyperalgesia in TrkA/C monoarthritic mice. This pain modulation was associated with a decrease of 99mTc-HMDP accumulation in the pathologic paw but no difference concerning 99mTc-NTP 15-5 accumulation in TrkA/C mice compared to WT mice.  Conclusion: The present study demonstrates a specific involvement of NGF/TrkA signaling in pain, especially mechanotransduction and an impact of the NGF/TrkA signaling pathways modulation on bone remodeling in inflammatory arthritis.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-491236" status="OLD">
          <idno type="IdRef">195779916</idno>
          <idno type="RNSR">201220182P</idno>
          <orgName>Neuro-Dol</orgName>
          <orgName type="acronym">Neuro-Dol</orgName>
          <date type="start">2017-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>UFR Médecine Pharmacie, TSA 50400, 28 Place Henri Dunant, 63001 Clermont-Ferrand // Faculté de Chirurgie Dentaire, 2 Rue de Braga, 63100 Clermont-Ferrand</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://neurodol.uca.fr/</ref>
          </desc>
          <listRelation>
            <relation name="U1107" active="#struct-303623" type="direct"/>
            <relation name="UMR1107" active="#struct-422708" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-490689" status="OLD">
          <idno type="IdRef">23549738X</idno>
          <idno type="RNSR">201722539E</idno>
          <orgName>Imagerie Moléculaire et Stratégies Théranostiques</orgName>
          <orgName type="acronym">IMoST</orgName>
          <date type="start">2017-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>58, Rue Montalembert, 63005 Clermont-Ferrand</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://imost.uca.fr</ref>
          </desc>
          <listRelation>
            <relation name="U1240" active="#struct-303623" type="direct"/>
            <relation name="UMR1240" active="#struct-422708" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-199397" status="VALID">
          <idno type="IdRef">149374186</idno>
          <idno type="RNSR">201220316K</idno>
          <idno type="ROR">02me5cy06</idno>
          <orgName>Institut de Biologie du Développement de Marseille</orgName>
          <orgName type="acronym">IBDM</orgName>
          <date type="start">2016-01-01</date>
          <desc>
            <address>
              <addrLine>Case 907 - Parc Scientifique de Luminy 13288 Marseille Cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ibdm.univ-mrs.fr</ref>
          </desc>
          <listRelation>
            <relation name="UMR7288" active="#struct-198056" type="direct"/>
            <relation active="#struct-300026" type="direct"/>
            <relation name="UMR7288" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-422708" status="OLD">
          <idno type="IdRef">196200032</idno>
          <idno type="ROR">https://ror.org/01a8ajp46</idno>
          <orgName>Université Clermont Auvergne [2017-2020]</orgName>
          <orgName type="acronym">UCA  [2017-2020]</orgName>
          <date type="start">2017-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>49, bd François-Mitterrand / CS 60032 / 63001 Clermont-Ferrand Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.uca.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-198056" status="VALID">
          <idno type="IdRef">15863621X</idno>
          <idno type="ISNI">0000 0001 2176 4817</idno>
          <idno type="ROR">https://ror.org/035xkbk20</idno>
          <orgName>Aix Marseille Université</orgName>
          <orgName type="acronym">AMU</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-amu.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300026" status="VALID">
          <orgName>Collège de France</orgName>
          <orgName type="acronym">CdF (institution)</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>