Insulin Adsorption onto PE and PVC Tubings - Université Clermont Auvergne Accéder directement au contenu
Article Dans Une Revue ACS Applied Bio Materials Année : 2022

Insulin Adsorption onto PE and PVC Tubings

Résumé

We investigate the adsorption of insulin onto PE and PVC materials by using HPLC measurements and computer simulations. We interpret the experiments by calculating the Gibbs free energy profiles during the adsorption process. The values of free energy of adsorption show a good agreement with the experimental measurements. The adsorption of insulin onto the different materials is characterized through the conformational changes with respect to its conformation in water and the interfacial regions, which are described by specific arrangements of polymer chains, water, insulin, and plasticizer molecules.
Fichier principal
Vignette du fichier
pub3-v4.pdf (16.79 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03682647 , version 1 (31-05-2022)

Identifiants

Citer

Nicolas Tokhadzé, Meriem Sahnoune, Julien Devémy, Alain Dequidt, Florent Goujon, et al.. Insulin Adsorption onto PE and PVC Tubings. ACS Applied Bio Materials, 2022, ⟨10.1021/acsabm.2c00029⟩. ⟨hal-03682647⟩
81 Consultations
126 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More