Amino acids as regulators of gene expression in mammals: Molecular mechanisms - Université Clermont Auvergne Accéder directement au contenu
Article Dans Une Revue Prostaglandins, Leukotrienes and Essential Fatty Acids Année : 2009

Amino acids as regulators of gene expression in mammals: Molecular mechanisms

Résumé

In mammals, the impact of nutrients on gene expression has become an important area of research. Because amino acids have multiple and important functions, their homeostasis has to be finely maintained. However, amino acidemia can be affected in some nutritional conditions and by various forms of stress. Consequently, mammals have to adjust physiological functions involved in the adaptation to amino acid availability. Part of this regulation involves the modulation of numerous gene expression. It has been shown that amino acids by themselves can modify the expression of target genes. This review focuses on the recent advances in the understanding of the mechanisms involved in the control of mammalian gene expression in response to amino acid limitation.

Dates et versions

hal-02664128 , version 1 (31-05-2020)

Identifiants

Citer

Alain Bruhat, Yoan Chérasse, Cédric Chaveroux, Anne-Catherine Maurin, Céline Jousse, et al.. Amino acids as regulators of gene expression in mammals: Molecular mechanisms. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2009, 35 (3), pp.249-257. ⟨10.1002/biof.40⟩. ⟨hal-02664128⟩
9 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More