Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model - Université Clermont Auvergne Accéder directement au contenu
Article Dans Une Revue International Journal for Vitamin and Nutrition Research Année : 2007

Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model

Résumé

Long-term thiamine deficiency has been largely documented, whilst little I is known about effects of short-term, depletion/repletion period on thiamine vitamers status. Rats were submitted to short-term depletion (8 days) followed by different durations of repletion (3 or 14 days) with thiamine from bread (whole wheat bread or white bread; whole B and white B respectively) or corresponding controls. Short-term depletion drastically decreased plasma thiamine (-97%) and its urinary excretion (-77%). TDP (thiamine diphosphate) was strongly affected in liver (-67%) but less affected in cerebellum(-38%),or kidneys (-45%). Short-term repletion (3 days) with whole B diet or its control restored TDP at initial values in cerebellum and kidneys. A longer repletion (14 days) was required to restore liver TDP. Comparison of the diet groups indicates that thiamine status in tissues of rat fed whole B or, white B diet was comparable to! that of rats fed purified thiamine. Plasma thiamine I concentration could not be restored at initial values in the bread groups or respective controls. In conclusion, thiamine in whole wheat bread appears effective in preventing marginal deficiencies and plasma thiamine is a less reliable indicator of thiamine status than tissue TDP levels.
Fichier non déposé

Dates et versions

hal-02658144 , version 1 (30-05-2020)

Identifiants

Citer

Frederique Batifoulier, Marie-Anne Verny, Catherine Besson, Elisabeth Chanliaud, Christian Remesy, et al.. Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model. International Journal for Vitamin and Nutrition Research, 2007, 77 (1), pp.46-56. ⟨10.1024/0300-9831.77.1.46⟩. ⟨hal-02658144⟩
10 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More