Retinoic acid and tracheal occlusion for diaphragmatic hernia treatment in rabbit fetuses - Université Clermont Auvergne Accéder directement au contenu
Article Dans Une Revue Prenatal Diagnosis Année : 2018

Retinoic acid and tracheal occlusion for diaphragmatic hernia treatment in rabbit fetuses

Amelie Delabaere
  • Fonction : Auteur
  • PersonId : 1038626
Karen Coste
Gael Clairefond
  • Fonction : Auteur
Pierre Blanc
  • Fonction : Auteur
  • PersonId : 762282
  • IdRef : 191241105
Vincent Sapin

Résumé

Lung hypoplasia and pulmonary arterial hypertension in congenital diaphragmatic hernia lead to a high perinatal mortality. Although sustained fetoscopic tracheal occlusion (TO) improves lung development, a major side effect is abnormal pneumocyte differentiation. This study evaluated the potential ability of intratracheal retinoic acid (RA) administration to reduce adverse effects of sustained TO in a rabbit model of diaphragmatic hernia.
Fichier non déposé

Dates et versions

hal-01918664 , version 1 (11-11-2018)

Identifiants

Citer

Amelie Delabaere, Loïc Blanchon, Karen Coste, Gael Clairefond, Corinne Belville, et al.. Retinoic acid and tracheal occlusion for diaphragmatic hernia treatment in rabbit fetuses. Prenatal Diagnosis, 2018, 38 (7), pp.482 - 492. ⟨10.1002/pd.5256⟩. ⟨hal-01918664⟩
79 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More