%0 Journal Article %T Success rates in smoking cessation: Psychological preparation plays a critical role and interacts with other factors such as psychoactive substances %+ Hôpital Sud-Fancilien %+ Dispensaire Émile Roux %+ Service Biostatistiques et Informatique Médicale (CHU de Dijon) (DIM) %+ Université de Lille, Droit et Santé %+ Neuro-Psycho Pharmacologie des Systèmes Dopimanégiques sous-corticaux (NPsy-Sydo) %A Joly, Bertrand %A Perriot, Jean %A D’athis, Philippe %A Chazard, Emmanuel %A Brousse, Georges %A Quantin, Catherine %< avec comité de lecture %@ 1932-6203 %J PLoS ONE %I Public Library of Science %S PLoS One %V 12 %N 10 %8 2017-10-11 %D 2017 %R 10.1371/journal.pone.0184800 %M 29020085 %Z Life Sciences [q-bio] %Z Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology %Z Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior %Z Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesJournal articles %X BACKGROUND: The aim of this study was to identify factors associated with the results of smoking cessation attempts.METHODS: Data were collected in Clermont-Ferrand from a smoking cessation clinic between 1999 and 2009 (1,361 patients). Smoking cessation was considered a success when patients were abstinent 6 months after the beginning of cessation. Multivariate logistic regression was used to investigate the association between abstinence and different factors.RESULTS: The significant factors were a history of depression (ORadjusted = 0.57, p = 0.003), state of depression at the initial consultation (ORa = 0.64, p = 0.005), other psychoactive substances (ORa = 0.52, p<0.0001), heart, lung and Ear-Nose-Throat diseases (ORa = 0.65, p = 0.005), age (ORa = 1.04, p<0.0001), the Richmond test (p<0.0001; when the patient's motivation went from insufficient to moderate, the frequency of abstinence was twice as high) and the Prochaska algorithm (p<0.0001; when the patient went from the 'pre-contemplation' to the 'contemplation' level, the frequency of success was four times higher). A high score in the Richmond test had a greater impact on success with increasing age (significant interaction: p = 0.01). In exclusive smokers, the contemplation level in the Prochaska algorithm was enough to obtain a satisfactory abstinence rate (65.5%) whereas among consumers of other psychoactive substances, it was necessary to reach the preparation level in the Prochaska algorithm to achieve a success rate greater than 50% (significant interaction: p = 0.02).CONCLUSIONS: The psychological preparation of the smoker plays a critical role. The management of smoking cessation must be personalized, especially for consumers of other psychoactive substances and/or smokers with a history of depression. %G English %2 https://uca.hal.science/hal-01691033/document %2 https://uca.hal.science/hal-01691033/file/journal.pone.0184800.pdf %L hal-01691033 %U https://uca.hal.science/hal-01691033 %~ PRES_CLERMONT %~ ACL-SVSAE %~ NPSY-SYDO %~ CHU-CLERMONTFERRAND %~ EPOTEC