Subthalamic Nucleus Location: Relationships between Stereotactic AC-PC-Based Diagrams and MRI Anatomy-Based Contours

Subthalamic nucleus (STN) targeting is classically performed based on AC-PC probabilistic position. Nevertheless, MRI allows direct visualization and targeting. We aimed to compare the position localized on MR images with standard stereotactic diagrams. The STN was manually contoured on MR images (22 Parkinson's disease patients); boundaries were simplified in a schematic polygonal form. Front and lateral stereotactic diagrams were constructed according to Talairach and Benabid. We compared x, y and z coordinates of the geometrical center of MRI-based polygons and stereotactic diagrams (Wilcoxon matched-pairs tests). There was significant discordance between MRI-based polygons and AC-PCbased images. MRI shows the STN as more posterior, medial and slightly inferior.

Keywords

Subthalamic nucleus targeting Deep brain stimulation Stereotactic AC-PC-based diagrams

Domains

Neurobiology Signal and Image processing

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Caire_StereotactFunctNeurosurg_2009.pdf (943.76 Ko)

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Jérôme Coste : Connect in order to contact the contributor

https://uca.hal.science/hal-01552987

Submitted on : Monday, July 3, 2017-1:02:41 PM

Last modification on : Monday, September 2, 2024-2:46:04 PM

Long-term archiving on : Thursday, December 14, 2017-9:13:16 PM

Dates and versions

hal-01552987 , version 1 (03-07-2017)

Identifiers

HAL Id : hal-01552987 , version 1
DOI : 10.1159/000236367

Cite

François Caire, Lemlih Ouchchane, Jerome Coste, Jean Gabrillargues, Philippe Derost, et al.. Subthalamic Nucleus Location: Relationships between Stereotactic AC-PC-Based Diagrams and MRI Anatomy-Based Contours. Stereotactic and Functional Neurosurgery, 2009, 87, pp.337 - 347. ⟨10.1159/000236367⟩. ⟨hal-01552987⟩

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